All photography by Alison McDonald-Spakes.

ALS Quick Facts

  • The average life expectancy of a person with ALS is two to five years from time of diagnosis.
  • On average, someone is diagnosed every 90 minutes with ALS.
  • Military veterans are approximately twice as likely to develop ALS.
  • Because there is no known cause for most forms of ALS, there is no cure.

WHY 447?

The 447 Foundation is a non-profit 501(c)3 organization created in memory of my wife Alison McDonald-Spakes who passed away from ALS (Amyotrophic Lateral Sclerosis) 447 days after being diagnosed. I made a promise to her that I would do all I could to raise funds and awareness to annihilate ALS.

We have partnered with the ALS Therapy Development Institute to support their research for treatments and ultimately to find a cure for this terrible disease.



They are the world's foremost drug discovery center focused solely on ALS. As a nonprofit biotech they operate without regard to profit motive or politics. Led by people with ALS and drug development experts, they are funded by a global network of supporters unified to ending ALS in our lifetime.

Donate Now